PRISMA-Children and Adolescents (PRISMA-C) 2026

The PRISMA-Children and Adolescents (PRISMA-C) 2026 statement is an extension of PRISMA 2020. It is designed to facilitate comprehensive reporting of systematic reviews focused on evaluating the effects of interventions for children and adolescents (ages 0-19 years). PRISMA-C 2026 also applies to systematic reviews that involve a mixed population (e.g. children and adults), parent/child dyads, and when parents/caregivers are receiving or delivering the intervention, but the outcomes and effectiveness of the intervention are assessed in children or adolescents.

Key documents

• Checklist: PDF

• Statement and explanation paper: Baba A, Farid-Kapadia M, Smith M, Hartling L, Moher D, Hooft L, Offringa M. PRISMA-Children and Adolescents (PRISMA-C) 2026 extension statement and explanation: enhancing the reporting and utility of systematic reviews of interventions in paediatrics. BMJ 2026;393:e088561. doi: 10.1136/bmj-2025-088561.

• More information and resources can be found at https://lab.research.sickkids.ca/enrich/reporting-standards/prisma-c-prisma-pc/