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TRANSPARENT REPORTING of SYSTEMATIC REVIEWS and META-ANALYSES

In this section you can find out more about the PRISMA Statement, obtain downloads of PRISMA documents, find out more about PRISMA development, and information about funding. We have adopted the definitions of systematic review and meta-analysis used by the Cochrane Collaboration. A systematic review is a review of a clearly formulated question that uses systematic and explicit methods to identify, select, and critically appraise relevant research, and to collect and analyze data from the studies that are included in the review. Statistical methods (meta-analysis) may or may not be used to analyze and summarize the results of the included studies. Meta-analysis refers to the use of statistical techniques in a systematic review to integrate the results of included studies.

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